The influence of the muscarinic receptor subtypes on the sleep-wake cycle

Angeli, P.; Bianchi, S.; Imeri, L.; Mancia, M.

Farmaco 48(9): 1197-1206

1993


ISSN/ISBN: 0014-827X
PMID: 8259978
Document Number: 409878
The specific role played by different muscarinic receptor subtypes in sleep regulation is investigated and discussed. On the basis of the results obtained with intracerebroventricular injections of selective muscarinic antagonists into freely moving rats, it is suggested that each muscarinic receptor subtype induces different and specific changes in sleep phases and cortical desynchronization processes.

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