Epidural meperidine for control of autonomic hyperreflexia in a quadriplegic undergoing cystoscopy
Baraka, A.; Noueihid, R.; Sibai, A.N.; Baroody, M.; Louis, F.; Hemady, K.
Middle East Journal of Anaesthesiology 10(2): 185-188
1989
ISSN/ISBN: 0544-0440 PMID: 2811779 Document Number: 4092
Epidural meperidine was used to control autonomic hyperreflexia (AH) during cystoscopy and transuretheral sphincterotomy, in a quadriplegic patient who had chronic spinal cord transection at C6 level. Meperidine 100 mg diluted in 10 ml saline was injected in the epidural space at L3-L4 level. Within 10 minutes and throughout the surgical procedure, the blood pressure stabilized at 125/70-140/80 mmHg. Epidural meperidine produces selective blockade of the spinal opiate receptors and hence may block the nociceptive reflexes below the level of cord transection and prevent AH.
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