Application of electron microscopy and immunocytochemistry in lung cancer diagnosis
Przybyłowski, P.; Młynarczyk, W.; Błotna-Filipiak, M.; Biczysko, W.
Folia Morphologica 52(4): 191-200
1993
ISSN/ISBN: 0015-5659 PMID: 8175072 Document Number: 407474
Using bronchofiberoscopy the biopsies of '50 small cell carcinomas of the lung (SCLC) were diagnosed. The material was studied by immunocytochemical methods for cytokeratins and in routine transmission electron microscopy. The presence of bundles of cytokeratins was specific for squamous epithelium, in all histological subtypes of small cell carcinomas. The number and distribution of cytokeratins were described. In whole material we found the neuroendocrine cells in which polymorphic neuroendocrine granules were present.