The effect of oral medroxyprogesterone acetate and methyltestosterone on sexual functioning in a male contraceptive trial
Doody, K.; Bain, J.
Contraception 31(1): 65-70
1985
ISSN/ISBN: 0010-7824 PMID: 3157547 DOI: 10.1016/0010-7824(85)90075-7Document Number: 407441
Men (23)who participated in a 15- mo. clinical trial to assess the potential effectiveness of using a combination of varying doses of medroxyprogesterone acetate (MPA) and methyltesterone (MT) as a male contraceptive agent, completed a "sexual problem checklist" every 2 wk. The study was divided into 3 phases: pre-treatment (3 mo.), treatment (6 mo.), post-treatment (6 mo.). The questionnaire evaluated changes in various aspects of sexual behavior and sexual perception and explored whether the treatment influenced any of the parameters considered. The results indicated a small, but significant, decrease in subjective assessment of sexual drive. This was not, however, accompanied by a change in sexual behavior, in that subjects experienced the same number of erections, ejaculations and frequency of intercourse. The combination of MPA and MT in the doses used may produce a slight decrease in subjective assessment of sexual drive, but no change in actual sexual behavior.