VDT pulse magnetic field enhances teratogenic effect of ara-c in mice

Chiang, H.

Zhonghua Yu Fang Yi Xue Za Zhi 27(4): 215-217

1993


ISSN/ISBN: 0253-9624
PMID: 8143517
Document Number: 407440
Impregnated NIH mice were irradiated 4 hrs daily on days 16th-17th of gestation with 15.6 kHz pulse magnetic field at 40 microT peak to peak. Significant enhancement of ara-c induced teratogenic potency by the magnetic field can be observed. The incidence of harelip fetuses bearing harelip and/or cleft palate was significantly higher in the combined exposure group, in which mice were exposed to the magnetic field and given an intraperitoneal injection of ara-c on the 9th day of gestation, than that of mice treated with ara-c alone.

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