Segregation ratio and heritability of lung cancer in Xuanwei County, China
Jin, Y.T.; He, X.Z.
Zhonghua Yi Xue Za Zhi 73(12): 753
1993
ISSN/ISBN: 0376-2491 PMID: 8143194 Document Number: 406313
To determine the relation between genetic factor and lung cancer We selected 370 lung cancer probands in Xuanwei county, Yunan Province China. The data on 370 nuclear families were analysed. The segregation ratio of lung cancer was 0.15 and the genetic model of lung cancer belonged to polygenetics. The heritability of lung cancer was 24.6%, 14.6% for male and 37.8% for female. It is concluded that genetic factor is one of the risk factors for lung cancer is specially of importance for females, but it is not a main risk factor for lung cancer. Our results are helpful in complaining the high incidence of lung cancer in females in Xuanwei county.