Experimental transmission of an apparent viral pneumonia in conventional and gnotobiotic pigs
Halbur, P.G.; Paul, P.S.; Andrews, J.J.; Sanderson, T.P.; Ross, R.F.; Schwartz, K.J.; Frey, M.L.; Erickson, B.J.; Hill, H.T.; Hoffman, L.J.
Veterinary Record 132(11): 263-266
1993
ISSN/ISBN: 0042-4900 PMID: 8465501 Document Number: 406193
Endemic pneumonia in 5- to 8-week-old pigs induced microscopic lesions of proliferative interstitial pneumonia which were compatible with a viral aetiology. The disease was transmitted experimentally to conventional and gnotobiotic pigs by means of a lung homogenate filtered through a 0.22 micro m filter. No common viral respiratory pathogens of pigs were isolated. Two types of virus particles were observed in cell culture by electron microscopy; one was about 70 nm in diameter and had an envelope and short surface spicules, the other also had an envelope, was elongated, pleomorphic, measured 80 x 320 nm and was coated by antibodies.