Silastic gel and elastomer in the cicatrization of wounds in the rabbit
Aubert, J.P.; Magalon, G.
Journal de Chirurgie 130(12): 533-538
1993
ISSN/ISBN: 0021-7697 PMID: 8163619 Document Number: 405556
The aim of this experimental study was to examine two new wound healing adjuvants. Four experimental wounds were created on the back of rabbits to compare the kinetics of wound healing after applying the standard treatment, Silastic gel, and elastomer with and without compounds known to act on wound healing. We observed a tendency towards more rapid healing in the gel groups (13.7 days), the elastomer group (17.3 days) and the elastomer with active compound group (15.3 days) compared with the control group (17.3 days) and the standard treatment group (17.8 days). The differences were not however statistically different. Elastomer is the better carrier for active wound healing compounds because it has better stability over time. Silicon dressings are interesting for wound healing because they give satisfactory results in terms of healing time and in terms of redressing and patient comfort.