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Borna disease in ostriches

Malkinson, M.; Weisman, Y.; Ashash, E.; Bode, L.; Ludwig, H.

Veterinary Record 133(12): 304

1993

ISSN/ISBN: 0042-4900
PMID: 8204140
Document Number: 405502
The detection of Borna disease virus (BDV) specific antigen in 7 of 13 brains from birds with a spastic paretic condition and from the brain of one healthy bird from a farm with diseased birds is reported. Antigen was detected by a highly sensitive modified ELISA. By co-cultivation of tissues from an infected bird with several cell lines, viral antigen was also detected by immunofluorescence at the fourth serial passage using adult ostrich serum and confirmed with a monoclonal mouse antibody. The virus showed no cytopathogenic effects. This is the first report of natural Borna disease in ostriches.

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