Evaluation of the usefulness of cerebral perfusion pressure in threatened cerebral ischemia
Stepińska, G.; Czernicki, Z.; Berdyga, J.
Neurologia i Neurochirurgia Polska Suppl. 1: 243-250
1992
ISSN/ISBN: 0028-3843 PMID: 1407305 Document Number: 404646
The Cushing response was produced using the lumbar infusions in cats. The following parameters were recorded and computed: arterial blood pressure (ABP), central venous pressure (CVP), intracranial pressure (ICP), heart rate and ECG. The lactate concentration was studied in brain stem and brain cortex. The analysis of ABP and ICP recordings showed in some cases that the Cushing response was obtained at CPP over 60 mmHg. The role of adrenergic reaction in Cushing phenomenon was confirmed by the increase in blood catecholamine concentration and typical adrenergic changes in ECG pattern.