Effect of cryoconservation of platelets on polyamine level and cathepsin D activity
Kovtunova, M.E.; Selezneva, O.M.; Vorozhtsova, S.I.; Kunof, V.K.
Voprosy Meditsinskoi Khimii 38(1): 33-36
1992
ISSN/ISBN: 0042-8809 PMID: 1441290 Document Number: 404048
Alterations in activity of cathepsin D as well as in content of polyamines spermine, spermidine, x-fraction (apparently, acetyl spermidine) and putrescine were studied in blood platelets depending on conditions of conservation. The enzyme activity and content of polyamines correlated directly with duration of the cell concentrates storage. Cathepsin D and polyamines appear to be involved in responses to stress adaptation.