CT-guided stereotactic injection of radionuclide in treatment of brain tumors
Tian, Z.M.; Liu, Z.H.; Kang, G.Q.; Li, S.Y.; Wang, Y.G.; Diao, G.P.; Dong, G.Z.
Chinese Medical Journal 105(12): 987-991
1992
ISSN/ISBN: 0366-6999 PMID: 1338588 Document Number: 403879
140 patients with brain tumors were treated by CT-guided stereotactic injections of radionuclides, such as Aurum-198 (198 Au), Phosphorus-32 (32 P) and Yttrium-90 (90Y). Of those patients aged from 3 to 67 years (average 37), 64 were male and 76 female. Astrocytoma was found in 75 patients, craniopharyngioma in 46, metastatic carcinoma in 7, meningioma in 5, germinoma in 4 and pituitary adenoma in 3. The tumors were located in the deep part or functionally critical area of the brain. After 267 times of injection of colloidal isotopes, no major adverse effects or complications occurred. Follow-up for 6 to 48 months showed improvement in symptoms in 104 (74.3%) patients and CT scanning showed the diminished tumors.