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Metabolic consequences of long-term antihypertensive treatment with co-dergocrine mesylate/nifedipine in high age groups

Ritter, M.M.; Richter, W.O.; Schwandt, P.

Arzneimittel-Forschung 42(3): 311-313

1992

ISSN/ISBN: 0004-4172
PMID: 1497690
Document Number: 403170
Possible metabolic changes during chronic treatment is of specific importance for the development of antihypertensive drugs. The impact of a combination treatment with co-dergocrine mesilate/nifedipine (Pontuc; CAS 8067-24-1 resp. CAS 21829-25-4) on the lipid metabolism as well as hematological and biochemical values was evaluated in a group of hypertensive patients. HDL-cholesterol remained unchanged, whereas total cholesterol and LDL-cholesterol slightly decreased, apoprotein AI increased and apoprotein B decreased. In conclusion the results of this study indicate that co-dergocrine mesilate/nifedipine has no negative impact on the lipid metabolism in patients with essential hypertension.

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Kitamura, S. 1980: The treatment of asthmatic patients using an alpha-adrenergic receptor blocking agent, co-dergocrine mesylate ('Hydergine') Pharmatherapeutica 2(5): 330-336
Agabiti-Rosei, E.; Muiesan, M.L.; Geri, A.; Romanelli, G.; Beschi, M.; Castellano, M.; Muiesan, G. 1988: Long-term antihypertensive treatment may induce normalization of left ventricular mass before complete regression of vascular structural changes: consequences for cardiac function at rest and during stress Journal of Hypertension. Supplement: Official Journal of the International Society of Hypertension 6(4): S94-S96
Apperloo, A.J.; de Zeeuw, D.; de Jong, P.E. 1994: Short-term antiproteinuric response to antihypertensive treatment predicts long-term GFR decline in patients with non-diabetic renal disease Kidney International. Suppl 45: S174-S178
Peleska, J.; Jindra, A.; Jáchymová, M.; Zvárová, J.; Savliková, J.; Jarolim, M. 1987: Humoral changes during a long-term antihypertensive treatment Agents and Actions. Supplements 22: 191-196
Lette, J.; Gagnon, R.M.; Lemire, J.G.; Morissette, M. 1984: Rebound of vasospastic angina after cessation of long-term treatment with nifedipine Canadian Medical Association Journal 130(9): 1169-1171; 1174
Nicrosini, F.; Pasotti, C. 1983: Long-term treatment with a new antihypertensive drug: flutonidin Minerva Medica 74(21): 1297-1300
Toftdahl, D.B.; Andersen, G.S. 1989: Effect of long-term nifedipine treatment on body fluid composition in essential hypertension Journal of Human Hypertension 3(3): 203-206
Khosseĭn, A.; Mukharliamov, N.M.; Mareev, V.I.; Lobova, N.M.; Ageev, F.T. 1988: Long-term use of the calcium antagonist nifedipine (corinfar) in the treatment of patients with primary pulmonary hypertension Kardiologiia 28(4): 54-58
Zawada, E.T.; Williams, L.; McClung, D.E.; TerWee, J.A.; Horning, J.; McNulty, R.; Thomas, M.; Simmons, J. 1987: Renal-metabolic consequences of antihypertensive therapy with diltiazem versus hydrochlorothiazide Mineral and Electrolyte Metabolism 13(2): 72-77
Zeher, M.; Antal, L.; Azad, A.Q.; Szegedi, G. 1988: Examination of the antihypertensive action of long-term estulic (Egis-Sandoz) treatment Therapia Hungarica 36(3): 103-108
Hansen, H.P.; Nielsen, F.S.; Rossing, P.; Jacobsen, P.; Jensen, B.R.; Parving, H.H. 1997: Kidney function after withdrawal of long-term antihypertensive treatment in diabetic nephropathy Kidney International. Suppl 63: S49-S53
Włodarczyk, A.; Bielecki, K.; Tałałaj, M.; Marcinowska-Suchowierska, E.; Zawadzki, J.; Ciok, M.; Gajda, A.; Brzozowski, R. 1994: Long-term consequences of surgical treatment of peptic ulcer Materia Medica Polona. Polish Journal of Medicine and Pharmacy 26(1): 13-16
Striuk, R.I.; Brytkova, I.V.; Bukhonkina, I.M.; Pavlova, L.N. 2008: Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol Kardiologiia 48(4): 29-33
Fujii, S.; Kaku, K.; Andou, S.; Nakayama, H.; Suetsugu, N.; Inoue, M.; Yoshizaki, Y.; Matsuda, M.; Tanaka, M.; Okafuji, S. 1993: Glucose and lipid metabolism during long-term antihypertensive treatment with indapamide in non-insulin-dependent diabetic patients Clinical Therapeutics 15(6): 1041-1050
Oliván, J.; Miranda, M.J.; Chozas, J.; Gras, B.X.; Garrido, M. 1985: Long-term efficacy of captopril in the treatment of moderate/intensive arterial hypertension resistant to 3 antihypertensive drugs Medicina Clinica 85(14): 571-574
Hosie, J.; Nasar, M.A.; Belgrave, G.P.; Walters, E.G. 1994: A comparative study of long acting diltiazem (Tildiem LA) with sustained release nifedipine (nifedipine SR) and bendrofluazide in the treatment of mild to moderate hypertension Acta Cardiologica 49(3): 251-265
Seidl, O.; Keller, C. 1981: Experiences in the long-term treatment of metabolic diseases Zfa. Zeitschrift für Allgemeinmedizin 57(14): 1060-1064
Pogorzelska, H.; Rawczyńska-Englert, I.; Hoffman, M.; Sokołowska-Bruszewska, E.; Marcisz-Szufladowicz, E.; Zelenay, M.; Abramczuk, E.; Bieganowski, A.; Madeja, G.; Orłowska, E. 1990: Consequences of late diagnosis and long-term conservative treatment of patients with congenital heart defects Kardiologia Polska 33(6): 351-357
Tonooka, T.; Takiguchi, N.; Yamamoto, H.; Nabeya, Y.; Ikeda, A.; Kainuma, O.; Souda, H.; Cho, A.; Muto, Y.; Yanagibashi, H.; Takano, E.; Denda, T.; Nagata, M. 2014: A case of rectal gastrointestinal stromal tumor (GIST) locally resected after long-term chemotherapy with imatinib mesylate Gan to Kagaku Ryoho. Cancer and ChemoTherapy 41(12): 1849-1851
1982: Comparison of propranolol and hydrochlorothiazide for the initial treatment of hypertension. II. Results of long-term therapy. Veterans Administration Cooperative Study Group on Antihypertensive Agents JAMA 248(16): 2004-2011