Effect of pregnancy associated hypertension on immunoglobulin levels in newborns
Sharma, R.; Nandi, D.; Shukla, I.; Maheshwari, V.
Indian Pediatrics 29(5): 581-586
1992
ISSN/ISBN: 0019-6061 PMID: 1500106 Document Number: 402618
In a prospective study of 124 neonates born to mothers with normal pregnancy and pregnancy associated hypertension (PAH), serum IgG, IgA and IgM were estimated by single radial immunodiffusion technique. Significantly low levels of IgG were found in mothers having PAH, as compared to normal pregnancy (p less than 0.001), whereas IgA and IgM showed no difference in the two groups. There was no statistical difference in maternal and cord blood IgG in either the control or study group. IgG was significantly higher (p less than 0.001) in cord blood of babies born by vaginal route as compared to forceps (via vaginal route) or cesarean section. IgA and IgM levels did not vary with mode of delivery.