Prediction of susceptibility to rheumatoid arthritis by human leukocyte antigen genotyping
Nepom, G.T.; Nepom, B.S.
Rheumatic Diseases Clinics of North America 18(4): 785-792
1992
ISSN/ISBN: 0889-857X PMID: 1455045 Document Number: 402537
Recent methodologic advances now allow the precise identification of HLA genes in individuals. Population studies using these methods have pinpointed the HLA alleles strongly associated with rheumatoid arthritis (RA). This article summarizes the current status of these RA-associated HLA genes in disease susceptibility and uses that information to derive estimates of risk ratios for prediction of disease in an individual.
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