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Vitamin B 12 metabolism and the status of sulfhydryl groups in protein-choline deficiency in rats. Effects of methyl- and adenosylcobalamins

Tsukerman, E.S.; Korsova, T.L.; Poznanskaia, A.A.

Voprosy Pitaniia 1: 40-44

1992

ISSN/ISBN: 0042-8833
PMID: 1621377
Document Number: 401001
The effect of low protein choline-deficient diet on total vitamin B12 content and individual cobalamin level in the blood serum and liver of rats was determined. Moreover the total and non-protein SH-group content and glutathione transferase activity in the liver of rats were studied. Total cobalamin content increased in the blood serum, but it did not change in the liver of rats fed choline-deficient low protein diet. Total and non-protein SH-group level as well as glutathione transferase activity in the liver decreased significantly. The causes of changes revealed are discussed. Methylcobalamin (but not adenosylcobalamin) administration normalized individual cobalamin level in the blood serum. Administration of both methylcobalamin and adenosyl-cobalamin resulted in total SH-group content restoration whereas non-protein SH-group level and glutathione transferase activity were restored only in methylcobalamin-treated rats.

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Akeson, P.K.; Casswall, T.; Kull, I. 2012: Risk of vitamin D deficiency among certain groups in Sweden. new recommendations can be considered--optimal vitamin D status still unknown Lakartidningen 109(26-28): 1285-1289
Bankson, D.D.; Russell, R.M. 1988: Protein energy malnutrition and taurine supplementation: effects on vitamin A nutritional status and electroretinogram of young rats Journal of Nutrition 118(1): 23-32
Hoover, K.L.; Lynch, P.H.; Poirier, L.A. 1984: Profound postinitiation enhancement by short-term severe methionine, choline, vitamin B12, and folate deficiency of hepatocarcinogenesis in F344 rats given a single low-dose diethylnitrosamine injection Journal of the National Cancer Institute 73(6): 1327-1336
McKay, M.J.; Bond, J.S. 1985: Oxidation of protein sulfhydryl groups as an initial event in protein degradation Progress in Clinical and Biological Research 180: 351-361
Pekkanen, T.J.; Sandholm, M. 1971: The effect of experimental methyl mercury poisoning on the number of sulfhydryl (SH) groups in the brain, liver and muscle of rat Acta Veterinaria Scandinavica 12(4): 551-559
Shi, R.; Wang, C.; Lan, L.; Han, W.; Xu, X.; Wang, K.; Liu, B. 2009: Effect of iron deficiency on vitamin a metabolism in rats Wei Sheng Yan Jiu 38(5): 535-537
Nikonorow, M.; Urbanek-Karlowska, B.; Karlowski, K. 1977: Effect of protein deficiency in rats on the activity of selected enzymes participating in protein and carbohydrate metabolism Roczniki Panstwowego Zakladu Higieny 28(1): 1-8
Woodard, J.C. 1970: Effects of deficiencies in labile methyl groups on the growth and development of fetal rats Journal of Nutrition 100(10): 1215-1225
Baeten, J.M.; Richardson, B.A.; Bankson, D.D.; Wener, M.H.; Kreiss, J.K.; Lavreys, L.; Mandaliya, K.; Bwayo, J.J.; McClelland, R.Scott. 2004: Use of serum retinol-binding protein for prediction of vitamin A deficiency: effects of HIV-1 infection, protein malnutrition, and the acute phase response American Journal of Clinical Nutrition 79(2): 218-225
Jope, R.S. 1982: Effects of phosphatidylcholine administration to rats on choline in blood and choline and acetylcholine in brain Journal of Pharmacology and Experimental Therapeutics 220(2): 322-328
Kazantseva, I.A. 1972: Protein sulfhydryl groups in hyperplastic and neoplastic laryngeal epithelium Voprosy Onkologii 18(3): 31-33
Jennings, G.; Elia, M. 1991: Independent effects of protein and energy deficiency on acute-phase protein response in rats Nutrition 7(6): 430-434
Iavors'kyĭ, O.G. 1994: Non-protein sulfhydryl groups in the blood of patients with stenocardia induced by physical stress Ukrainskii Biokhimicheskii Zhurnal 66(3): 85-89
Kazantseva, I.A.; Krut'kovskaia, N.P. 1971: A microspectrophotometric study of the concentration of protein sulfhydryl groups in endometrial gland epithelium in hyperplasia and cancer Biulleten' Eksperimental'noi Biologii i Meditsiny 71(3): 79-81
Burns, R.A.; Jackson, N. 1982: The metabolism of [3',5',9(n)-3H] pteroylglutamic acid by chicken liver in vivo. Effects of folate deficiency and vitamin B12 supplementation International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift für Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition 52(2): 149-158
Shimamoto, N.; Goto, N.; Hirata, M. 1982: Effects of 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone (CV-2619) on the energy metabolism of red blood cells of rats Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 80(2): 137-145
Nakajima, T.; Ichikawa, S.; Uchida, S.; Komada, T. 1990: Effects of a protein-bound polysaccharide from a basidiomycetes against hepatocarcinogenesis induced by 3'-methyl-4-dimethylaminoazobenzene in rats Clinical Therapeutics 12(5): 385-392
Abdraimova, S.M.; Koshkenbaev, B.K.; Maksimenko, V.B.; Tazhibaev, S.S. 1985: Hypokinesia, nutrition and lipid metabolism. the effect of protein-vitamin deficiency on serum lipids and lipoproteins in hypokinesia Voprosy Meditsinskoi Khimii 31(5): 87-91
Gorstein, J.; Shreshtra, R.K.; Pandey, S.; Adhikari, R.K.; Pradhan, A. 2003: Current status of vitamin A deficiency and the National Vitamin A Control Program in Nepal: results of the 1998 National Micronutrient Status Survey Asia Pacific Journal of Clinical Nutrition 12(1): 96-103
Vasnetsova, S.S.; Kulik, G.I.; Korol', V.I.; Turkevich, N.M. 1977: Hormonal sensitivity of mammary adenocarcinoma in rats and the capacity of the sulfhydryl groups of this tumor for bindig by various antineoplastic drugs Voprosy Onkologii 23(5): 91-94