Structure and function of oligosaccharide chains of the envelope glycoprotein gp120 of human immunodeficiency virus type 1
Mizuochi, T.
Nihon Rinsho. Japanese Journal of Clinical Medicine 50(6): 1419-1429
1992
ISSN/ISBN: 0047-1852 PMID: 1518160 Document Number: 400245
The surface of the human immunodeficiency virus (HIV-1), a causative agent for acquired immunodeficiency syndrome (AIDS), is covered with the major envelope glycoprotein gp120, of which the carbohydrate moiety accounted for 50% of the molecular mass. There is evidence that glycosylation of gp120 is prerequisite to the various stages of HIV infection. The oligosaccharide structures of gp120 have been determined using recombinant gp120 of HIV-1 (IIIB) produced in chinese hamster ovary cells and virus-derived gp120 isolated from H9 lymphocytes chronically infected with HIV-1 (IIIB). Three oligosaccharides have been suggested to be involved in the HIV-infection process. Occurrence of infection process which is independent of CD4 recognition and mediated by gp120 oligosaccharides, mannose-binding protein, and complement system has been suggested.
Document emailed within 1 workday
Related Documents
Vitale, F.; Russo Alesi, D.; Bonura, F.; Di Benedetto, M.A.; Mammina, C.; Romano, N. 1991: Change in size of the envelope glycoprotein of a human immunodeficiency virus 1 (HIV 1) strain Microbiologica 14(1): 15-20Thali, M.; Furman, C.; Wahren, B.; Posner, M.; Ho, D.D.; Robinson, J.; Sodroski, J. 1992: Cooperativity of neutralizing antibodies directed against the V3 and CD4 binding regions of the human immunodeficiency virus gp120 envelope glycoprotein Journal of Acquired Immune Deficiency Syndromes 5(6): 591-599
Huang, M.L.; Essex, M.; Lee, T.H. 1991: Localization of immunogenic domains in the human immunodeficiency virus type 2 envelope Journal of Virology 65(9): 5073-5079
Wiktor, S.Z.; Pate, E.J.; Murphy, E.L.; Palker, T.J.; Champegnie, E.; Ramlal, A.; Cranston, B.; Hanchard, B.; Blattner, W.A. 1993: Mother-to-child transmission of human T-cell lymphotropic virus type I (HTLV-I) in Jamaica: association with antibodies to envelope glycoprotein (gp46) epitopes Journal of Acquired Immune Deficiency Syndromes 6(10): 1162-1167
Lund, J.; Takahashi, N.; Pound, J.D.; Goodall, M.; Jefferis, R. 1996: Multiple interactions of IgG with its core oligosaccharide can modulate recognition by complement and human Fc gamma receptor I and influence the synthesis of its oligosaccharide chains Journal of Immunology 157(11): 4963-4969
Jones, W.C.; Barnard, A.L.; Slade, A.; Mills, K.H. 1992: Heterogeneity in the recognition of the simian immunodeficiency virus envelope glycoprotein by CD4+ T cell clones from immunized macaques Journal of Immunology 149(9): 3120-3126
Machado, A.A.; Hirsch, I.; Figueiredo, J.F.; Martinez, R.; de Freitas-Silva, G.; Chermann, J.C.; Covas, D.T. 1996: Occurrence of false positives in tests with synthetic peptides for the analysis of antibodies against the human immunodeficiency virus type 2 (HIV-2) in Brazilian patients infected with the human immunodeficiency virus type 1 (HIV-1) Revista da Sociedade Brasileira de Medicina Tropical 29(6): 615-617
Miao, F.; Li, C.; Zhang, S.; Wang, X.-f.; Li, J.-d.; Zhang, Q.-f.; Liu, Q.-z.; Wei, Y.; Hang, X.-t.; Liang, M.-f.; Li, D.-x. 2009: Secreted expression of dengue virus type i envelope glycoprotein in 293T cells Zhonghua Shi Yan he Lin Chuang Bing du Xue Za Zhi 23(6): 415-417
Balzarini, J.; Velazquez, S.; San-Felix, A.; Karlsson, A.; Perez-Perez, M.J.; Camarasa, M.J.; De Clercq, E. 1993: Human immunodeficiency virus type 1-specific [2',5'-bis-O-(tert- butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"- oxathiole-2",2"-dioxide)-purine analogues show a resistance spectrum that is different from that of the human immunodeficiency virus type 1-specific non-nucleoside analogues Molecular Pharmacology 43(1): 109-114
Yusim, K.; Peeters, M.; Pybus, O.G.; Bhattacharya, T.; Delaporte, E.; Mulanga, C.; Muldoon, M.; Theiler, J.; Korber, B. 2001: Using human immunodeficiency virus type 1 sequences to infer historical features of the acquired immune deficiency syndrome epidemic and human immunodeficiency virus evolution Philosophical Transactions of the Royal Society of London. Series B Biological Sciences 356(1410): 855-866
Kline, M.W.; Lewis, D.E.; Hollinger, F.B.; Reuben, J.M.; Hanson, L.C.; Kozinetz, C.A.; Dimitrov, D.H.; Rosenblatt, H.M.; Shearer, W.T. 1994: A comparative study of human immunodeficiency virus culture, polymerase chain reaction and anti-human immunodeficiency virus immunoglobulin A antibody detection in the diagnosis during early infancy of vertically acquired human immunodeficiency virus infection Pediatric Infectious Disease Journal 13(2): 90-94
Koyanagi, A.; Humphrey, J.H.; Ntozini, R.; Nathoo, K.; Moulton, L.H.; Iliff, P.; Mutasa, K.; Ruff, A.; Ward, B.; Chidawanyika, H.; Hargrove, J.; Mahomva, A.I.; Majo, F.; Malaba, L.C.; Mbizvo, M.T.; Mzengeza, F.; Ndhlovu, M.; Piwoz, E.; Propper, L.; Rambanepasi, P.; Ruff, A.J.; Tavengwa, N.; Zijenah, L.S.; Zunguza, C.D.; Zvandasara, P. 2011: Morbidity among human immunodeficiency virus-exposed but uninfected, human immunodeficiency virus-infected, and human immunodeficiency virus-unexposed infants in Zimbabwe before availability of highly active antiretroviral therapy Pediatric Infectious Disease Journal 30(1): 45-51
Haishi, S.; Imai, H.; Hirai, K.; Igarashi, A.; Kato, S. 1989: Expression of envelope glycoprotein (E) of Japanese encephalitis virus by recombinant vaccinia virus Acta Virologica 33(6): 497-503
Marx, P.A.; Munn, R.J.; Joy, K.I. 1988: Computer emulation of thin section electron microscopy predicts an envelope-associated icosadeltahedral capsid for human immunodeficiency virus Laboratory Investigation; a Journal of Technical Methods and Pathology 58(1): 112-118
Nagot, N.; Ouedraogo, A.; Konate, I.; Weiss, H.A.; Foulongne, V.; Defer, M.C.; Sanon, A.; Becquart, P.; Segondy, M.; Sawadogo, A.; Van de Perre, P.; Mayaud, P.; Bahembera, E.; Berthe, A.; Coulibaly, M.; Defer, M.-C.; Diallo, R.; Djagbare, D.; Konate, I.; Ky-Dama, F.; M'Boutiki, G.T.; Meda, N.; Millogo, I.; Ouedraogo, A.; Ouedraogo, D.; Rouet, F.ço.; Sanon, A.; Sawadogo, H.; Vallo, R.; Andonaba, J.-B.; Sawadogo, A.; Mayaud, P.; Weiss, H.A.; Nagot, N.; Becquart, P.; Foulongne, V.; Segondy, M.; Van de Perre, P. 2008: Roles of clinical and subclinical reactivated herpes simplex virus type 2 infection and human immunodeficiency virus type 1 (HIV-1)-induced immunosuppression on genital and plasma HIV-1 levels Journal of Infectious Diseases 198(2): 241-249
Okuku, H.Selassie.; Sanders, E.J.; Nyiro, J.; Ngetsa, C.; Ohuma, E.; McClelland, R.Scott.; Price, M.A.; Graham, S.M. 2011: Factors associated with herpes simplex virus type 2 incidence in a cohort of human immunodeficiency virus type 1-seronegative Kenyan men and women reporting high-risk sexual behavior Sexually Transmitted Diseases 38(9): 837-844
Lusso, P.; Markham, P.D.; Ranki, A.; Earl, P.; Moss, B.; Dorner, F.; Gallo, R.C.; Krohn, K.J. 1988: Cell-mediated immune response toward viral envelope and core antigens in gibbon apes (Hylobates lar) chronically infected with human immunodeficiency virus-1 Journal of Immunology 141(7): 2467-2473
Dominguez, M.C.; Castillo, A.; Cabrera, J.; Eizuru, Y.; Garcia-Vallejo, F. 2002: Envelope sequence variation and phylogenetic relations of human T cell lymphotropic virus type 1 from endemic areas of Colombia Aids Research and Human Retroviruses 18(12): 887-890
Chu, F.-l.; Wen, H.-l.; Hou, G.-h.; Lin, B.; Zhang, W.-q.; Song, Y.-y.; Ren, G.-j.; Sun, C.-x.; Li, Z.-m.; Wang, Z.-y. 2013: Study on functions of N-carbohydrate chains in human parainfluenza virus type 3 hemagglutinin-neuraminidase protein Bing du Xue Bao 29(5): 500-508
Cremer, K.; Wohlenberg, C.; Notkins, A.L.; Mackett, M.; Moss, B. 1985: Vaccinia virus recombinant that expresses the herpes simplex virus type 1 glycoprotein d gene protects mice against lethal challenge by herpes simplex virus type 1 or herpes simplex type 2 and the establishment of a latent ganglionic infection by herpes simplex virus type 1 Lerner, R A , R M Chanock And F Brown (Ed ) Vaccines 85: Molecular And Chemical Basis Of Resistance to Parasitic, Bacterial, And Viral Diseases; Meeting, 1983 Xxi+407p Cold Spring Harbor Laboratory: Cold Spring Harbor, N Y , Usa Illus Paper 169-174