Determination of moxalactam, aztreonam and imipenem by the perchloric hydroxylamine method
Pajchel, G.; Borowiecka, B.; Chojnowski, W.
Acta Poloniae Pharmaceutica 49(1-2): 7-10
1992
ISSN/ISBN: 0001-6837 PMID: 8769073 Document Number: 399549
The reaction of perchloric hydroxylamine was adopted for determination of new beta-lactam antibiotics within monobactam, carbapenem and oxazepam groups. Complexes formed in colour reaction are stable over 2 hours in the case of aztreonam and imipenem, and over 1 hour for moxalactam, statistical analysis proved that both hydroxylamine-perchloric and spectrophotometric methods can be used alternatively.
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