Experimental model of liver metastases of the mouse
Ban, S.
Nihon Geka Hokan. Archiv für Japanische Chirurgie 61(1): 62-66
1992
ISSN/ISBN: 0003-9152 PMID: 1530382 Document Number: 396521
3 syngeneic tumor-mouse systems were used to establish experimental model of liver metastasis. Only one system, SC42-DS, was suitable for the purpose. When 2 .times. 105 SC42 tumor cells was injected into the spleen of DS mouse and splenectomy was done after 24 hours preventing of spleen tumor due to inplantation, multiple nodular liver metastasis were observed in all mice afte 14 days. The numbers of nodule were well correlated with the liver weight.
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