Hematuric cystitis after bone marrow allograft: a case
Bontemps, I.; Frappaz, D.; Levignes, F.; Freycon, F.
Pediatrie 47(7-8): 525-529
1992
ISSN/ISBN: 0031-4021 PMID: 1336164 Document Number: 394276
A 16-year-old boy experienced a severe macroscopic hemorrhagic cystitis 20 days after a partially mismatched allogeneic marrow transplantation for an acute lymphoblastic leukemia. The conditioning included cyclophosphamide and total body irradiation. After a conservative management, the hematuria spontaneously resolved after 3 months of gross hematuria. The authors review the literature, and stress the predisposing factors and clinical outcome of such complication. They advocate a conservative "watch-and-wait" approach including intensive bladder irrigation.