Changes of luminol-dependent chemiluminescence of rabbit peripheral blood leukocytes during incubation with a specific allergen during the development of Arthus phenomenon
Pytskiĭ, V.I.; Filatov, O.N.
Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 1992(5-6): 41-43
1992
ISSN/ISBN: 0031-2991 PMID: 1284611 Document Number: 393012
The authors studied luminol-dependent chemiluminescence of rabbit peripheral blood leukocytes during the development of Arthus' phenomenon. Samples with a specific allergen were previously incubated. It was established that in this type of allergic reactions the intensity of leukocyte chemiluminescence was determined by the concentration of the allergen with which they were incubated. Small doses of the allergen stimulate and large doses inhibit it. The inhibition is linked with the direct effect of the allergen on the cells and is not attended with diminution of their viability.