Expression of alpha-melanocyte stimulating hormone and the invasive ability of the B16 murine melanoma
Zubair, A.; Lakshmi, M.S.; Sherbet, G.V.
Anticancer Research 12(2): 399-402
1992
ISSN/ISBN: 0250-7005 PMID: 1580557 Document Number: 392821
The expression of alpha melanocyte stimulating hormone (MSH) has been investigated in two variants of the B16 murine melanoma. The presence of MSH was demonstrated by immunohistochemical methods using anti-MSH antibodies. The low metastasis variant B16-F1, which grows as an encapsulated non-invasive tumour, showed no alpha-MSH immunoreactivity. In contrast, the high metastasis variant BL6 was found to be alpha-MSH positive and the immunoreactivity was found predominantly in the peripheral invading zones of the tumour.
Document emailed within 1 workday
Related Documents
Bhardwaj, R.; Becher, E.; Mahnke, K.; Hartmeyer, M.; Schwarz, T.; Scholzen, T.; Luger, T.A. 1997: Evidence for the differential expression of the functional alpha-melanocyte-stimulating hormone receptor MC-1 on human monocytes Journal of Immunology 158(7): 3378-3384Orias, R. 1968: Effect of hypothalamic extracts and stress on the pituitary melanocyte stimulating hormone content in rats abstract in vitro rana pipiens skin follicle stimulating hormone luteinizing hormone growth hormone oxytocin hormone vasopressin hormone Proceedings Int Union Physiology Science 7(24): 332
Orias, R. 1968: Effect of hypothalamic extracts and stress on the pituitary melanocyte stimulating hormone content in rats abstract in vitro rana pipiens skin follicle stimulating hormone luteinizing hormone growth hormone oxytocin hormone vasopressin hormone Proceedings Int Union Physiology Science 7(24): 332
Katsuki, A.; Sumida, Y.; Murashima, S.; Furuta, M.; Araki-Sasaki, R.; Tsuchihashi, K.; Hori, Y.; Yano, Y.; Adachi, Y. 2000: Elevated plasma levels of alpha-melanocyte stimulating hormone (alpha-MSH) are correlated with insulin resistance in obese men International Journal of Obesity and Related Metabolic Disorders: Journal of the International Association for the Study of Obesity 24(10): 1260-1264
Vdovenko, V.M.; Dil'man, V.M.; Bobrova, V.N.; Patokin, S.V. 1970: Production of iodine-131 labelled melanocyte stimulating hormone and its distribution in mice with melanoma Voprosy Onkologii 16(4): 91-93
Remy, W.; Rakoski, J.; von Mayenburg, J. 1989: Local pigment stimulation by alpha-melanocyte stimulating hormone in the human: intracutaneous injections without and with ultraviolet irradiation Zeitschrift für Hautkrankheiten 64(6): 459-460
Hughes-Darden, C.A.; Wachira, S.J.; Batta, E.; Ochillo, R.; Robinson, T.J. 2001: Effects of gamma-2-melanocyte-stimulating hormone on protein kinase C activity and expression in spontaneous hypertensive rats (SHR) Cellular and Molecular Biology 47(6): 1069-1075
Willemse, T.; Vroom, M.W.; Mol, J.A.; Rijnberk, A. 1993: Changes in plasma cortisol, corticotropin, and alpha-melanocyte-stimulating hormone concentrations in cats before and after physical restraint and intradermal testing American Journal of Veterinary Research 54(1): 69-72
Goudreau, J.L.; Lookingland, K.J.; Moore, K.E. 1994: 5-Hydroxytryptamine2 receptor-mediated regulation of periventricular-hypophysial dopaminergic neuronal activity and the secretion of alpha-melanocyte-stimulating hormone Journal of Pharmacology and Experimental Therapeutics 268(1): 175-179
Eaton, M.J.; Tian, Y.; Lookingland, K.J.; Moore, K.E. 1992: Comparison of the effects of remoxipride and raclopride on nigrostriatal and mesolimbic dopaminergic neuronal activity and on the secretion of prolactin and alpha-melanocyte-stimulating hormone Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 7(3): 205-211
Kastin, A.J.; Barbeau, A.; Ehrensing, R.H.; Plotnikoff, N.P.; Schally, A.V. 1974: Melanocyte-stimulating hormone and the hypothalamic hormone which inhibits its release Advances in Neurology 5: 225-229
Kato, Y. 2010: Lipotropin (lipotropic hormone: LPH) and melanocyte-stimulating hormone (MSH) Nihon Rinsho. Japanese Journal of Clinical Medicine 68(Suppl 7): 234-236
Fabrikant, J.; Touloei, K.; Brown, S.M. 2013: A review and update on melanocyte stimulating hormone therapy: afamelanotide Journal of Drugs in Dermatology: Jdd 12(7): 775-779
Smith, A.G.; Shuster, S.; Thody, A.J.; Peberdy, M. 1977: Chloasma, oral contraceptives, and plasma immunoreactive beta-melanocyte-stimulating hormone Journal of Investigative Dermatology 68(4): 169-170
Rannevik, G.; Jeppsson, S.; Kullander, S.; Thorell, J. 1973: Effects of synthetic luteinizing hormone releasing hormone on plasma levels of luteinizing hormone follicle stimulating hormone and thyrotropin in amenorrheic women and comparison of luteinizing hormone and follicle stimulating hormone response after intra venous intra muscular and sublingual administration Acta Endocrinologica Supplementum 177: 293
Rivers, J.K.; Copley, M.R.; Svoboda, R.; Rigel, D.S. 2018: Non-Invasive Gene Expression Testing to Rule out Melanoma Skin Therapy Letter 23(5): 1-4
Mergenthaler, H.G.; Dörmer, P.; Staber, F.G.; Hültner, L. 1982: The effect of two different types of colony-stimulating factor on the expression of aminopeptidase on marrow-derived murine macrophages Experimental Hematology 10(9): 789-797
Gagnon, A.; Lochnan, H.A.; Tran, C.S.; Sorisky, A. 2016: Thyroid-stimulating hormone acutely increases monocyte gene expression in vivo Neuro Endocrinology Letters 37(2): 121-123
Goldman, J.M.; Hadley, M.E. 1972: Sulfhydryl requirement for alpha adrenergic receptor activity and melanophore stimulating hormone (MSH) action on melanophores Journal of Pharmacology and Experimental Therapeutics 182(1): 93-100
Castelli, C.; Sensi, M.; Lupetti, R.; Mortarini, R.; Panceri, P.; Anichini, A.; Parmiani, G. 1994: Expression of interleukin 1 alpha, interleukin 6, and tumor necrosis factor alpha genes in human melanoma clones is associated with that of mutated N-RAS oncogene Cancer Research 54(17): 4785-4790