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Comparison of sodium valproate and phenytoin as single drug treatment in generalised and partial epilepsy

Rastogi, P.; Mehrotra, T.N.; Agarwala, R.K.; Singh, V.S.

Journal of the Association of Physicians of India 39(8): 606-608

1991

ISSN/ISBN: 0004-5772
PMID: 1814875
Document Number: 3927
Ninety four patients of generalised and partial epilepsy were randomly assigned to treatment with sodium valproate (49 cases) or phenytoin (45 cases). Serum levels were monitored. Cases were evaluated after 4, 12, 24 weeks of treatment. Both drugs were found to be equally effective in controlling generalised seizures. However, valproate is better in partial seizures. No correlation could be established. Side effects were minor with both the drugs.

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Comparison of sodium valproate and phenytoin as single drug treatment in generalised and partial epilepsy

Mehrotra, T.N.; Aneja, G.K.; Arora, V.; Goel, S.; Singh, V.S. 1990: Valproate sodium in epilepsy. a clinical trial including monitoring of drug levels Journal of the Association of Physicians of India 38(4): 277-279
Bilikiewicz, A.; Rudy, B. 1978: Our experiences in the treatment of epilepsy with sodium valproate (convulex) Psychiatria Polska 12(5-6): 623-625
Watanabe, Y.; Watanabe, K.; Ohtsuka, Y. 2011: Aggravation of epilepsy by valproate sodium in a child with cryptogenic localization-related epilepsy No to Hattatsu 43(1): 51-55
Levy, R.H.; Moreland, T.A. 1984: Clinical pharmacokinetics of sodium valproate, carbamazepine and phenytoin. Level-dose ration and interactions Schweizerische Rundschau für Medizin Praxis 73(6): 159-163
Otoom, S.; Bakhiet, M.; Khan, A.; Sequeira, R. 2006: Prolonged use of phenytoin, carbamazepine or valproate monotherapy on plasma levels of folate and B(12): a comparison between epileptic patients with or without cardiovascular disorders Neuro Endocrinology Letters 27(1-2): 85-88
Feuerstein, J.; Revol, M.; Roger, J.; Sallou, C.; Truelle, J.L.; Vercelletto, P.; Weber, M. 1983: Monotherapy with sodium valproate in generalized primary epilepsy. 2d phase: Study of long-term efficacy and tolerance La Semaine des Hopitaux: Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 59(16): 1263-1274
de la Torre, R.; murgía-Suarez, J.J.; Aldrete, J. 1980: Comparison of phenytoin and conventional drug therapy in the treatment of mild hypertension Clinical Therapeutics 3(2): 117-124
Elia, J.; Imbrogno, N.; Delfino, M.; Mazzilli, F. 2010: Retrograde ejaculation and abnormal hormonal profile in a subject under treatment with valproate and phenytoin Archivio Italiano di Urologia Andrologia: Organo Ufficiale di Societa Italiana di Ecografia Urologica e Nefrologica 82(4): 193-194
Kulkarni, C.; Vaz, J.; David, J.; Joseph, T. 1995: Aminophylline alters pharmacokinetics of carbamazepine but not that of sodium valproate--a single dose pharmacokinetic study in human volunteers Indian Journal of Physiology and Pharmacology 39(2): 122-126
Colburn, W.A.; Gibaldi, M. 1978: Prolonged impairment of the plasma-protein binding of phenytoin in the rat after a single dose of sodium oleate Drug Metabolism and Disposition: the Biological Fate of Chemicals 6(4): 452-455
Marescaux, C.; Micheletti, G.; Rumbach, L.; Warter, J.M. 1981: Confusional state after addition of a third antiepileptic drug to a phenobarbital-sodium valproate combination La Nouvelle Presse Medicale 10(15): 1237
Sapeika, N.; Kaplan, E.R. 1975: Effect of the antiepileptic drug sodium valproate on induction of hepatic microsomal P450 Research Communications in Chemical Pathology and Pharmacology 10(4): 767-768
Oliver, D.W.; Dormehl, I.C. 1998: Cerebral blood flow effects of sodium valproate in drug combinations in the baboon model Arzneimittel-Forschung 48(11): 1058-1063
Chassagnon, S. 2004: Medical and medico-social case management of drug-resistant partial epilepsy. Specific implementation of long-term antiepileptic treatment in the adult Revue Neurologique (Paris) 160(Special Issue 1): 5s315-5s326
Hernández, M.A.; Valencia, M.E.; Castillo, R.; Anciones, B. 1988: Sodium valproate in the treatment of choreoathetosis Medicina Clinica 90(12): 516
Rajna, P.; Veres, J.; Vitray, J. 1991: Place of phenytoin in treatment of resistant epilepsy Therapia Hungarica 39(1): 30-40
Yamamoto, T.; Yagi, S.; Kita, R.; Masui, H.; Kinoshita, H.; Sakamoto, Y.; Okada, K.; Miki, A.; Kondo, M.; Hashida, H.; Kobayashi, H.; Uryuhara, K.; Kaihara, S.; Hosotani, R. 2015: Comparison between anatomical subsegmentectomy and nonanatomical partial resection for hepatocellular carcinoma located within a single subsegment: a single-center retrospective analysis Hepato-Gastroenterology 62(138): 363-367
Auvichayapat, N.; Tassniyom, S.; Treerotphon, S.; Auvichayapat, P. 2007: Treatment of infantile spasms with sodium valproate followed by benzodiazepines Journal of the Medical Association of Thailand 90(9): 1809-1814
Visudhiphan, P. 2007: Treatment of infantile spasms with sodium valproate followed by benzodiazepines Journal of the Medical Association of Thailand 90(10): 2244
Warter, J.M.; Marescaux, C.; Chabrier, G.; Rumbach, L.; Micheletti, B.; Imler, M. 1984: Renal glutamine metabolism in man during treatment with sodium valproate Revue Neurologique (Paris) 140(5): 370-371