Study on diagnosis of hepatitis a by testing salivary IgM anti-HAV
Wang, Y.
Zhonghua Liu Xing Bing Xue Za Zhi 13(1): 9-11
1992
ISSN/ISBN: 0254-6450 PMID: 1316237 Document Number: 392025
The use of salivary samples to diagnose acute hepatitis A was investigated. Result indicated that IgM anti-HAV can be reliably detected in saliva of 58 cases with acute hepatitis A and 9 cases with mixed infection of hepatitis A and B. It is not present in saliva of individuals without recent hepatitis A including 84 cases with acute hepatitis B, 30 cases of hepatitis non A non B and 10 healthy individuals. It was suggested that use of salivary samples to diagnose hepatitis A was specific. It's concluded that saliva is a convenient and satisfactory alternative to serum for the clinical diagnosis and epidemiological investigation of hepatitis A infection.