Greater concentration of anti-hepatitis B antibodies (anti-HBs) in specific hyperimmune human gamma globulins (non-anti-hepatitis B) as compared with normal human gamma globulins

Picciotto, L.; Borgia, G.; De Mercato, R.; Piazza, M.

Bollettino della Societa Italiana di Biologia Sperimentale 56(4): 346-350

1980


ISSN/ISBN: 0037-8771
PMID: 6166305
Document Number: 168247
Twenty-seven lots of standard immunoglobulin from 5 different producers and 18 lots of specific immunoglobulin (non anti-Hepatitis B) were titrated by RIA test for anti-HBs content. The highest titre in lots of standard IG (1:40) was lower than the lowest titre of the lots of specific IG (non anti-Hepatitis B) (1:44). The difference between means (1:17 and 1:42) was statistically significant (p less then 0,01). The reasons for the difference are discussed.

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