Coma due to an overdose of valnoctamide

Melissant, C.F.; Vinks, A.A.; Sleeboom, H.P.

Nederlands Tijdschrift Voor Geneeskunde 136(16): 793-794

1992


ISSN/ISBN: 0028-2162
PMID: 1349428
Document Number: 390619
We report a 27-year-old man, who became comatose after autopoisoning with a high dose of valnoctamide. He was mechanically ventilated for 12 hours and survived without serious side effects. Valnoctamide blood levels were monitored in order to study the pharmacokinetics of oral overdosing of this drug. Serum half-time levels appeared to be approximately 15 hours.

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