Optimization of the conditions for extracting metronidazole with organic solvents
Belikov, V.G.; Vergeĭchik, T.K.; Tsybulina, M.G.
Sudebno-Meditsinskaia Ekspertiza 35(1): 22-23
1992
ISSN/ISBN: 0039-4521 PMID: 1589887 Document Number: 389311
Optimal conditions of metronidazole extraction from aqueous solutions by different solvents using a mathematical method of experiment planning (latin square) were studied. It was stated that optimal conditions of metronidazole extraction from aqueous solutions were: extraction time (5 min.), pH medium-6, extractant-isoamyl spirit in saturation of aqueous phase with ammonium sulfate.