Clinical significance of correction of serum beta 2-microglobulin levels for serum creatinine in multiple myeloma

Scudla, V.; Vavrdová, V.; Budíková, M.; Indrák, K.

Acta Universitatis Palackianae Olomucensis Facultatis Medicae 131: 257-264

1991


ISSN/ISBN: 0301-2514
PMID: 1840347
Document Number: 3890
In the group of 78 patients with multiple myeloma a comparison of the clinical significance of measured and corrected serum beta 2-microglobulin levels was carried out. There was confirmed a significant relationship between serum beta 2-microglobulin and serum creatinine levels. Pretreatment and follow-up of uncorrected serum beta 2-microglobulin levels were useful in confirming tumor mass grade (assessed according to Durie and Salmon or the British Medical Research Council) and survival prediction. No gain was evident from correcting the serum beta 2-microglobulin for the level of serum creatinine (according to Cassuto et al or Garewal et al).

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Clinical significance of correction of serum beta 2-microglobulin levels for serum creatinine in multiple myeloma