The role of dyslipoproteinemia in the genesis of chronic hepatitis
Klimenko, E.D.; Pozdniakov, O.M.
Biulleten' Eksperimental'noi Biologii i Meditsiny 114(10): 437-439
1992
ISSN/ISBN: 0365-9615 PMID: 1288717 Document Number: 388927
The dynamics of structural changes in the liver in experimental dyslipoproteinemia (DLP) and its correction was studied. Vessel-tissue changes found in the liver of rabbits in a short-term and stable DLP (4, 8 weeks) can be estimated as different stages of chronic active hepatitis. The microcirculation disorders and structural changes in the liver appeared at the early stages of DLP in the absence of atheromatosis in large arteries. The pathological changes in the liver existed 36 weeks after the rejection of atherogenic diet and correlated with DLP. Thus, DLP can be the risk factor as cardiovascular diseases as chronic nonspecific changes in the target organs.