Presence and significance of some antibodies/autoantibodies in patients with acute myocardial infarction and idiopathic dilated cardiomyopathy
Matache, C.; Stefănescu, M.; Ivanov, D.; Szegli, G.; Popescu, P.; Filip, Z.
Roumanian Archives of Microbiology and Immunology 51(4): 197-203
1992
ISSN/ISBN: 1222-3891 PMID: 1284800 Document Number: 387958
By using ELISA technique we determined the anti-myosin, actin, collagen type I and IV, cholesterol and phosphotyrosine proteins antibodies in sera from patients with acute myocardial infarction and idiopathic dilated cardiomyopathy. In idiopathic dilated cardiomyopathy we found a significant increase in five out of six types of antibodies tested. The patients with acute myocardial infarction reveal high levels of anti-myosin antibodies only. Our results suggest that some of the autoantibodies studied by us have a prognostic value and could be involved in maintaining cardiac dysfunctions.