The adverse effects induced by ornipressin during oral and maxillofacial surgical interventions under general anesthesia
Chiarini, L.; Cantoni, E.; Bettelli, G.; Mattioli, A.V.; Cappello, C.
Minerva Stomatologica 40(1-2): 77-79
1991
ISSN/ISBN: 0026-4970 PMID: 2041535 Document Number: 387324
There are various methods used in maxillofacial surgery for the control of superficial hemorrhage. The purpose is to achieve a better identification of the anatomical structures and reduce operating times without side effects. Ornipressin has no arrhythmogenic effects in presence of inhalational anesthetics and should therefore be considered safer then adrenalin. The authors examined the cardiocirculatory effects of this drug by means of an invasive hemodynamic study on five patients. The results showed that ornipressin causes worrying increases in blood pressure and peripheral vascular resistances, with reduction in the cardiac output.