Powdered alumina implants in the experimental animal: a histological study conducted in the rat
Di Silvestre, M.; Guizzardi, S.; Bettini, N.; Gargiulo, G.; Savini, R.
La Chirurgia Degli Organi di Movimento 76(2): 167-172
1991
ISSN/ISBN: 0009-4749 PMID: 1756677 Document Number: 387295
The authors present a histological study conducted in the rat after powdered alumina implantation in the subcutis, the muscle and the peritoneum. After two weeks the same intense acute inflammatory reaction was observed in all of the implantation sites. After eight weeks the inflammatory reaction had regressed: there was a thin layer of connective tissue around the implant, completely isolating it from the surrounding tissues.