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A low-dose combination oral contraceptive. Experience with 1,700 women treated for 22,489 cycles

Woutersz, T.B.

Journal of Reproductive Medicine 26(12): 615-620

1981

ISSN/ISBN: 0024-7758
PMID: 7033528
Document Number: 386886
A multicenter study was conducted to evaluate the efficacy and acceptability of a combination oral contraceptive containing norgestrel, 0.3 mg, and ethinyl estradiol, 0.03 mg. A total of 1,700 women were treated for 22,489 cycles. Only two pregnancies occurred (Pearl index, 0.20 per 100 woman-years). Cycle control was excellent, and the incidence of breakthrough bleeding, spotting and amenorrhea was low as compared to other reported series of similar low-dose combination contraceptives. No serious side effects were reported, and the drug had no demonstrable adverse effects on weight and blood pressure. The use of this low-dose oral contraceptive appears to provide effective birth control with a high laboratory index of safety and low incidence of side effects.

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Kallio, H.; Rhen, K. 1978: The contraceptive effects of a new low-dose combination type oral contraceptive Current Medical Research and Opinion 5(6): 444-449
Kallio, H.; Rhen, K. 1978: The contraceptive effects of a new low-dose combination type oral contraceptive Current Medical Research and Opinion 5(6): 444-449
Kuhnz, W.; al-Yacoub, G.; Fuhrmeister, A. 1992: Pharmacokinetics of levonorgestrel and ethinylestradiol in 9 women who received a low-dose oral contraceptive over a treatment period of 3 months and, after a wash-out phase, a single oral administration of the same contraceptive formulation Contraception 46(5): 455-469
Kaunitz, A.; Archer, D.; Foegh, M. 2012: Safety and tolerability of the agile patch, a contraceptive patch with low-dose ethinyl estradiol (EE) and levonorgestrel (LNG), vs. combination oral contraceptives (COCs) in obese vs. non-obese women Fertility and Sterility 98(3): S195-S196
O'Connell, K.J.; Osborne, L.M.; Westhoff, C. 2005: Measured and reported weight change for women using a vaginal contraceptive ring vs. a low-dose oral contraceptive Contraception 72(5): 323-327
1987: Clinical studies with a new, low-dose oral contraceptive combination, containing 0.150 mg desogestrel and 0.020 mg ethinylestradiol Acta obstetricia et gynecologica Scandinavica. Supplement 144: 1-44
Hanson, F.W.; Niswander, K.R. 1974: A new low dose norethindrone acetate (0.6 mg) ethinyl estradiol (30 mcg) combination oral contraceptive Journal of Reproductive Medicine 12(3): 109-111
Ramamoorthy, R.; Saraswathi, T.P.; Kanaka, T.S. 1989: Carbohydrate metabolic studies during twelve months of treatment with a low-dose combination oral contraceptive Contraception 40(5): 563-569
Morigi, E.M.; Pasquale, S.A. 1978: Clinical experience with a low dose oral contraceptive containing norethisterone and ethinyl oestradiol Current Medical Research and Opinion 5(8): 655-662
Akerlund, M. 1997: Clinical experience of a combined oral contraceptive with very low dose ethinyl estradiol Acta Obstetricia et Gynecologica Scandinavica. Suppl 164: 63-65
Ishak, R.; Ahmad, R.; Gudum, H.R.; Hassan, K.; Ang, E.S. 1992: Fibrinolytic response in women on low-dose oral contraceptive Malaysian Journal of Reproductive Health: a Publication of the Reproductive Research Centre of the National Population and Family Development Board Malaysia 10(1): 7-11
Weisberg, E.; Merki-Feld, G.S.; McGeechan, K.; Fraser, I.S. 2015: Randomized comparison of bleeding patterns in women using a combined contraceptive vaginal ring or a low-dose combined oral contraceptive on a menstrually signaled regimen Contraception 91(2): 121-126
Li, Y.; Gao, E.; Liu, Y.; Luo, L.; Wang, X.; Wang, H.; Wu, Y.; Zhou, L.; Sun, Z.; Zhang, L.; Wu, S.; Shia, J.; Macaluso, M.; McCarthy, B. 2002: Association between low-dose oral contraceptive use and stroke in Chinese women Zhonghua Yi Xue Za Zhi 82(15): 1013-1017
Cui, Y.; Zhu, H.; Zhu, Y.; Guo, X.; Huo, R.; Wang, X.; Tong, J.; Qian, L.; Zhou, Z.; Jia, Y.; Lue, Y.-H.; Hikim, A.S.; Wang, C.; Swerdloff, R.S.; Sha, J. 2008: Proteomic analysis of testis biopsies in men treated with injectable testosterone undecanoate alone or in combination with oral levonorgestrel as potential male contraceptive Journal of Proteome Research 7(9): 3984-3993
Uchikova, E.; Malinova, M.; Pekhlivanov, B.; Ledzhev, I. 2002: Hemostatic profile of women using low-dose oral contraceptive Mercilon. (Preliminary report) Akusherstvo i Ginekologiia 41(3): 23-25
Thomas, R.L.; Halvorson, L.M.; Carr, B.R.; Doody, K.M.; Doody, K.J. 2013: Efficacy of combined contraceptive vaginal ring versus oral contraceptive pills in achieving hypothalamic-pituitary-ovarian axis suppression in egg donor in vitro fertilization cycles Journal of Reproduction and Infertility 14(4): 207-213
Murphy, A.; Cropp, C.S.; Smith, B.S.; Burkman, R.T.; Zacur, H.A. 1990: Effect of low-dose oral contraceptive on gonadotropins, androgens, and sex hormone binding globulin in nonhirsute women Fertility and Sterility 53(1): 35-39
Gunson, M.J.; Arnett, G.W.; Formby, B.; Falzone, C.; Mathur, R.; Alexander, C. 2009: Oral contraceptive pill use and abnormal menstrual cycles in women with severe condylar resorption: A case for low serum 17β-estradiol as a major factor in progressive condylar resorption American Journal of Orthodontics and Dentofacial Orthopedics 136(6): 772-779
Anzai, Y.; Heger-Mahn, D.; Schellschmidt, I.; Marr, J. 2012: Suppression of ovarian activity with a low-dose 21/7-day regimen oral contraceptive containing ethinylestradiol 20 mcg/drospirenone 3 mg in Japanese and Caucasian women Contraception 86(1): 28-34
Caruso, S.; Rugolo, S.; Agnello, C.; Romano, M.; Cianci, A. 2009: Quality of sexual life in hyperandrogenic women treated with an oral contraceptive containing chlormadinone acetate Journal of Sexual Medicine 6(12): 3376-3384