Response of the pro- and antioxidant systems to plasmapheresis in patients with advanced atherosclerosis obliterans of the legs
Belotserkovskiĭ, M.V.; Dubikaĭtis, A.I.; Shabunevich, L.V.; Koniukhova, S.G.; Luk'ianov, I.V.; Shlomin, V.V.; Tokarevich, K.K.; Kylymnik, S.V.
Gematologiia i Transfuziologiia 36(9): 15-17
1991
ISSN/ISBN: 0234-5730 PMID: 1769502 Document Number: 386738
The effects of fractional apparatus plasmapheresis in a volume of 25% of circulating blood plasma on the processes of lipid peroxidation and on the antioxidant defence system parameters were studied in 31 patients with ischemia of the lower limbs, stage III-IV. It has been shown that plasmapheresis induces elevation of ceruloplasmin activity and superoxide dismutase activity of blood plasma, lowers the ratio of lipid oxidation to lipid peroxidation products simultaneously with intensification of lipid peroxidation that leads to regeneration of biological membranes of the body.