The effect of sulfur-containing preparations on the development of immediate allergization
Chetverikov, G.N.; Smirnova, V.V.; Demidova, M.A.
Farmakologiia i Toksikologiia 54(1): 43-46
1991
ISSN/ISBN: 0014-8318 PMID: 1860497 Document Number: 385694
The effects of sulfur-containing drugs and an inhibitor of sulfhydryl groups on the development of allergization of immediate type were studied. In experiments on rabbits and guinea pigs it was shown that the effects of sulfur-containing drugs depend on the dose, the stage of the allergic process. The donors of sulfhydryl groups significantly reduce anaphylactic shock and repeated allergic reactions of immediate type. The inhibitor of sulfhydryl groups produces the dose-dependent increase or decrease of the allergic reaction. The studied drugs change the dynamics of the content of sulfhydryl groups during sensitization.