The effect of potential antineoplastic antibiotics and the metal complex compound cisplatin on in vitro phagocytosis
Egerer, R.; Stelzner, A.; Süss, J.
Die Pharmazie 46(12): 872-874
1991
ISSN/ISBN: 0031-7144 PMID: 1818325 Document Number: 385085
Under standardized conditions the influence of the drugs lambdamycin, violamycin, granatomycin C, daunorubicin and cisplatin on the phagocytosis has been tested. Therapeutical doses of lambdamycin, daunorubicin and cisplatin did not have any obvious impairment on the phagocytosis. Contrarily to this granatomycin C (an isochromanchinon antibiotic) and violamycin (an anthracyclin in high concentrations) significantly depressed the phagocytosis of PMN.