Treatment of malignant trophoblastic tumors. An analysis of 209 cases
Wang, S.L.; Zhang, C.S.; Peng, H.Q.; Wu, K.H.
Chinese Medical Journal 104(2): 156-160
1991
ISSN/ISBN: 0366-6999 PMID: 1651828 Document Number: 383701
From 1984 to 1985, a total of 630 cases of choriocarcinoma and invasive mole were treated in our hospital. The methods of treatment varied in different periods of time. In the third period (1972-1985), 5 Fu and/or KSM were the main therapeutic agents used in the treatment of 110 cases of choriocarcinoma and 99 cases of invasive mole. Metastases were observed in more than 90% of cases of choriocarcinoma and nearly 1/4 belonged to stage IV. The mortality of choriocarcinoma decreased from 84.3% to 32.7% after treatment and that of invasive mole from 32.4% to 8.1%. 43 of 80 patients treated with chemotherapy alone conceived after recovery, resulting in a total of 50 pregnancies including 31 term deliveries by 28 women. All the children are normal and healthy, the eldest being 11 years old now.