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Pathogenetic mechanisms of stress-induced aggravation of experimental influenza and its prevention

Frolov, B.A.; Poliak, R.Ia.; Smagin, G.N.; Nikonorov, A.A.; Kul'divatov, I.Iu.; Chetverikova, L.K.; Inozemtseva, L.I.; Filippov, V.K.; Kramskaia, T.A.; Stadnikov, A.A.

Vestnik Akademii Meditsinskikh Nauk SSSR 1991(4): 50-54

1991

ISSN/ISBN: 0002-3027
PMID: 1866989
Document Number: 382121
It was stated that in stress-induced aggravation of infection realized in transformation of nonlethal patterns of infection into a lethal one there occurred a manifest dysfunction of hypothalamo-hypophyseal-neurosecretory performance (HHNS) featured by a 2-fold decrease in the blood vasopressin and an essential elevation of the hypothalamic one. The phenomenon is being suggestive of a possible blockage in the hormonal discharge into circulation and the limitation of its participation in the development of defensive and compensatory reactions. Identical HHNS dysfunction was noted in the lethal pattern of the infection. The authors formulated the concept of the main pathogenetic points underlying the damage of vegetative regulation centres. Mechanisms of viral and tissue metabolic damage of CNS were revealed. The authors substantiated the advisability and prospective use+ of antioxidants as applied to the prevention of severe course of influenza and its complications in extremely aggravated patterns.

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Classen, H.G.; Fischer, G.; Marx, J.; Schimatschek, H.; Schmid, C.; Stein, C. 1987: Prevention of stress-induced damage in experimental animals and livestock by monomagnesium-L-aspartate hydrochloride Magnesium 6(1): 34-39
Zager, R.A.; Gamelin, L.M. 1989: Pathogenetic mechanisms in experimental hemoglobinuric acute renal failure American Journal of Physiology 256(3 Pt 2): F446-F455
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Shishkina, L.N.; Safatov, A.S.; Sergeev, A.N.; Zhukov, V.A.; Bulychev, L.E.; P'iankov, O.V.; Poryvaev, V.D.; P'iankova, O.G.; Buriak, G.A.; Goncharova, E.P. 2001: Mechanisms of action of aerosol preparations based on Abies siberica polyprenols in experimental influenza infection Voprosy Virusologii 46(6): 28-33
Ul'ianinskiĭ, L.S.; Kosharskaia, I.L.; Starinskiĭ, I.G.; Beskrovnova, N.N.; Bogdanovich, N.K. 1986: Mechanisms of the development of the terminal state in experimental emotional stress Kardiologiia 26(5): 71-75
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Markushin, S.G.; Akopova, I.I.; Koptiaeva, I.B.; Tsfasman, T.M.; Gendon, I.Z. 2006: Molecular mechanisms of reversions to the ts+ -phenotype of cold-adapted influenza virus a strains--attenuation donors for live influenza reassortant vaccines Voprosy Virusologii 51(5): 17-22
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