Issues of adjuvant chemotherapy in gastric cancer: its clinical significance
Nakajima, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 18(6): 952-957
1991
ISSN/ISBN: 0385-0684 PMID: 2029198 Document Number: 381547
Though many previous reports suggest the clinical significance of adjuvant chemotherapy in gastric cancer, they are not always confirmed by the statistics. Treatment failures could be attributed to the minor benefit of chemotherapy for advanced cases, too much tumor burdens after surgery relative to the antitumor effect of chemotherapy, and statistically inadequate operation of clinical study. Improvement would be expected in the near future by carrying out a well designed control study with incorporation of new drugs such as CDDP or etoposide, or powerful regimen with MTX and 5 FU, or 5 FU and Leucovorin.