Intracerebral connections after administration of kainate into the caudal part of ventral sections of the medulla oblongata
Kul'chitskiĭ, V.A.; Taĭts, M.Iu.; Dudina, T.V.; Azev, O.A.; Kandybo, T.S.; Elkina, A.I.; Bazan, I.N.; Rozhnova, L.E.; Chelubeev, V.E.; Bol'shakova, V.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 112(12): 563-565
1991
ISSN/ISBN: 0365-9615 PMID: 1685678 Document Number: 381039
It was found that 1 day after unilateral destruction with kainate of neurons in the caudal ventral medulla unanesthetized animals showed disorders of arterial pressure control with a prevalence of hypertensive response. In 7 days after operation there was a decrease in the rate of neuronal uptake of serotonin and an increase in choline-, dopamine-, noradrenaline-, and glycinergic mediation in the basal hypothalamus and rostral ventral medulla, which characterize the functional state of synaptic formations in the brain stem structures connected to neurons in the caudal ventral medulla and involved in cardiovascular regulation.