Interaction code for polar and nonpolar amino acids: "ice-breaker" model
Chipens, G.I.; Rudzish, R.V.
Bioorganicheskaia Khimiia 17(11): 1445-1448
1991
ISSN/ISBN: 0132-3423 PMID: 1811540 Document Number: 380063
A novel model for the study of recognition and interaction code of amino acids in peptides, proteins and their complexes has been proposed. The model is designed on the modern notions on the structure and properties of water and hydrophobic bonds. It is assumed that the polar side chains of amino acids during the formation of the hydrophobic bonds act as "ice-breaker", thus destroying the organized structure of water (clusters or "icebergs") around the hydrophobic radicals of amino acids.