Long-term effect of cromolyn sodium on nonspecific bronchial hyperresponsiveness: a review
Hoag, J.E.; McFadden, E.R.
Annals of Allergy 66(1): 53-63
1991
ISSN/ISBN: 0003-4738 PMID: 1702945 Document Number: 379537
Long-term treatment with cromolyn sodium will reduce airway hyperresponsiveness in patients with bronchial asthma. Short-term use of cromolyn sodium (less than 6 weeks) is effective in preventing seasonal increases in allergen-induced hyperresponsiveness. Cromolyn sodium therapy for greater than 12 weeks appears to be beneficial in reducing baseline hyperresponsiveness. The effect of cromolyn sodium on bronchial hyperresponsiveness may result from its ability to stabilize mast cells. Other contributory properties of cromolyn sodium are reviewed.