The role of combined use of alpha-tocopherol, vitamin C and sodium nucleinate in normalization of the peroxidation processes and antioxidant activity of blood in acute pneumonia
Safarian, M.D.; Karagezian, K.G.
Klinicheskaia Meditsina 69(7): 93-96
1991
ISSN/ISBN: 0023-2149 PMID: 1942993 Document Number: 379432
The clinical effectiveness and the change characteristics of lipid peroxidation and antioxidant activity in the blood were assessed after the combined administration of alpha-tocopherol, vitamin C, and sodium nucleinate in acute pneumonia. One hundred ten men with acute focal pneumonia were divided into 4 treatment groups. The first received only traditional therapy (penicillin antibiotics, sulfanilamides, theophylline drugs, and expectorants). The second group received traditional therapy and both alpha-tocopherol and vitamin C, the third received traditional treatment in combination with sodium nucleinate, and the fourth received traditional therapy with alpha-tocopherol, vitamin C, and sodium nucleinate. The study showed that the effectiveness of traditional therapy including the separate administration of alpha-tocopherol, vitamin C, and sodium nucleinate was relatively high. However, the combined administration of these three substances increased the number of patients displaying clinical improvement to 97%.