The human genome: a view from above
Bernardi, G.
Bollettino della Societa Italiana di Biologia Sperimentale 67(5): 459-474
1991
ISSN/ISBN: 0037-8771 PMID: 1805878 Document Number: 379291
The genome of vertebrates (and of eukaryotes in general) is not simply formed by genes that are randomly scattered over vast expanses of "junk DNA", but is organized in a system which obeys precise rules, that amount to a genomic code. Moreover, genes are concentrated in the chromosomal regions which are the richest in G (guanine) and C (cytosine) and seem to correspond to the telomeric regions of certain chromosome arms (T-bands). The study of the genome organization in different vertebrate classes allowed us to approach in a novel way a number of fundamental problems of genome evolution.