Carbon disulfide excretion in urine--a biological exposure test for the workplace and environmental concentration ranges
Winkelmann, H.; Prösch, J.; Engewald, W.; Horn, K.
Zeitschrift für die Gesamte Hygiene und ihre Grenzgebiete 37(3): 102-104
1991
ISSN/ISBN: 0049-8610 PMID: 2038856 Document Number: 378909
The biological control procedure for carbon disulphide (CS2), the determination of free and bound CS2 in urine--a procedure already applied to hygienic surveillance--were modified by using gas chromatography and sulphide selective detection (FPD). The results obtained by the changed biological monitoring test in workplace and environmental surveillance are present and discussed. For CS2 concentrations at workplaces in the range of 8-54 mg/m3 a correlation coefficient of r = 0.56 (n = 11, p less than 0.07) was calculated for the mathematical connection of CS2 shift exposure and CS2 content in urine. For environmental exposures in the range of the CS2 immision short term threshold value (MIKK) of 0.03 mg/m3 the procedure may discriminate significantly exposure load from naturally occurring CS2 background.