Dysgerminoma of the ovary. Cytologic, histologic and electron microscopic study of a case
Hees, K.; de Jonge, J.P.; von Kortzfleisch, D.H.
Acta Cytologica 35(3): 341-344
1991
ISSN/ISBN: 0001-5547 PMID: 1710406 Document Number: 377147
A case of ovarian dysgerminoma is reported. Both histology and cytology showed cells with distinctive anisokaryosis and large, sometimes bizarre, nucleoli as the most striking feature. A lymphocytic infiltration was present. Electron microscopy showed large convoluted nucleoli, structures resembling so-called "annulated lamellae" and glycogen particles, features that are typical of a germ-cell tumor. The cytologic, histologic and ultrastructural investigations revealed a dysgerminoma; that diagnosis was not certain on the frozen sections.