Donovanosis: report of two cases with rare complications
Kumar, B.; Gupta, R.; Sharma, S.C.
Indian Journal of Sexually Transmitted Diseases 11(2): 68-70
1990
ISSN/ISBN: 0253-7184 PMID: 12343562 Document Number: 376791
2 cases of Donovanosis with unusual presentations, anal stricture in a 25-year old man, and massive enlargement of the labia in a 25-year old woman, are described. The man had a 15 x 6 cm laque from the natal cleft to the scrotum, constricting the anus so that he could only pass painful ribbon stools. The center was ulcerated for 4 cm around the anus. The patient had no other positive laboratory or clinical findings. The lesion had developed from a pustule that developed into an ulcerative lesion 7 years ago, just after a homosexual contact. A tissue smear, but no a biopsy, showed Donovan bodies. The patient was cured with 21 days of oral sulfamethoxazole-trimethoprim, 2 tablets of 400/80 mg twice daily. The woman's labia were both solidly enlarged and edematous, surrounded by ulceration of the groins and perineum. She also had no positive laboratory or systemic clinical findings. Her biopsy showed a few Donovan bodies, but repeated tissue smears were negative. Her ulcer was healed completely in 20 days with oral tetracycline, 2.0 g daily, but her labia remained swollen.