The presence of an ovarian granulocytic sarcoma concurrent with a type M2 acute myeloblastic leukemia: a case
Avigdor, S.; du Rouchet, E.; Michenet, P.; Grossetti, D.; Lucas, V.
Journal de Gynecologie Obstetrique et Biologie de la Reproduction 20(6): 797-801
1991
ISSN/ISBN: 0368-2315 PMID: 1822487 Document Number: 376728
The authors report a case of granulosa cell tumor principally located in the ovary associated with M2 type acute myeloblastic leukemia (AML) in a trisomy 22 patients. Surgery and chemotherapy were combined with a bone marrow allograft. Frequency of granulosa cell tumor is 8 percent or less of AML cases. Diagnosis is particularly difficult when haematologic expression occurs late in the disease course. An immunohistochemical work-up is required in these cases. Aetiopathogenesis is discussed. Treatment relies essentially on chemotherapy. The prognostic is variable according to different case reports in the literature.