Electron microscope-radioautography study of inveterate non-healing wounds
Smol'iannikova, V.A.; Kolokol'chikova, E.G.
Biulleten' Eksperimental'noi Biologii i Meditsiny 112(12): 647-650
1991
ISSN/ISBN: 0365-9615 PMID: 1777642 Document Number: 376048
Morphological and functional peculiarities of long non-healing wound granulation tissue cells have been studied. The cell functional and proliferating activities were defined by electron-microscopic radioautography of 3H-uridine and 3H-thymidine incorporation. There are few vessels and the lumens are narrow. The walls of the most of the vessels are in the state of destruction. There are multiple macrophages with phagosomes filled with detritus. Fibroblasts have endoplasmic reticulum with widened small canals. Not multiple collagen fibers have broken periodic striation.