Molecular biology studies of bladder cancer
Bringuier, P.P.; Knopf, H.J.; Schalken, J.A.; Debruyne, F.M.
Der Urologe. Ausg. a 30(3): 167-171
1991
ISSN/ISBN: 0340-2592 PMID: 1871935 Document Number: 375264
The mechanisms that control the biological behaviour of urothelial cancer are complex, and many regulative interactions are involved. So far, few aspects of these control mechanisms have been recognized and characterized. A precondition for better understanding is knowledge the interaction of this factors. Some markers (e.g., chromosomal aberrations, EGFR expression) are correlated with progression of tumour. Whether they are the cause or the result of the aggressive behaviour of growth remains unknown. Only a few markers, especially in flow cytometry, will have any benefit in clinical routine. Whether it is possible to find a marker with prognostic value remains uncertain.